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Ultrasound SmartBrief

High-output heart failure linked to increased risk in myelofibrosis

4/2/2026

Research published in Cardio-Oncology found that patients with myelofibrosis who had echocardiographic evidence of high-output heart failure had a 2.86 times greater risk of death or progression to leukemia. The study involved 114 patients across three medical centers from 2010 to 2024, using transthoracic echocardiography to define high-output heart failure. Rare Disease Advisor (4/1)

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